A study released in December 2008 by Fertility and Sterility, evaluated the outcome of women undergoing an intrauterine insemination (IUI) with clomiphene citrate (CC). The study examined over 4,100 cycles and found that age drastically impacted pregnancy rates. They found a significant drop in success rates for women aged 41-42. However, the drop for women over age 42 was so sharp that the study concluded, “CC with IUI has virtually no place in the treatment (of infertile women over age 42).”

Every cycle counts for women with advanced reproductive age. This study can help women and their doctors to make better treatment options for each cycle.

The study also found that pregnancy rates dropped for women undergoing a 3rd through 9th IUI cycle. Women were more likely to become pregnant if it was their first or second IUI cycle.